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Dosage Efficacy Interactions Prescribing Information Quality of Life Safety Information Testing and Method of Administration Patient Resource Materials
XALKORISupport & Services Prescribing Information Loading Efficacy Loading Quality of Life Loading
Abbreviations:ALK: anaplastic lymphoma kinase; ITT: intention-to-treat; NSCLC: non-small cell lung cancer; ORR: objective response rate; OS: overall survival; PFS: progression-free survival.References:Pfizer Laboratories (Pty) Ltd. XALKORI® 200 mg and 250 mg capsules Package Insert, approved 20 March 2018.Solomon BJ, Kim DW, Wu YL, et al. Final overall survival analysis from a study comparing first-line crizotinib versus chemotherapy in ALK-mutation-positive non-small-cell lung cancer. J Clin Oncol 2018;36(22):2251-2258.Solomon BJ, Mok T, Kim DW, et al. First-line crizotinib versus chemotherapy in ALK-positive lung cancer. N Engl J Med 2014;371(23):2167-2177.NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Non-Small Cell Lung Cancer V.6.2021. ©️ National Comprehensive Cancer Network, Inc. 2021. Accessed February 2022.Sullivan I, Planchard D. ALK inhibitors in non-small cell lung cancer: the latest evidence and developments. Ther Adv Med Oncol 2016;8(1):32-47.
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